Article
Associations between molecular characteristics of colorectal serrated polyps and subsequent advanced colorectal neoplasia.
Cancer causes & control : CCC - 1 Jul 2020
Hua Xinwei, Newcomb Polly A, Chubak Jessica, Malen Rachel C, Ziebell Rebecca, Kamineni Aruna, Zhu Lee-Ching, Upton Melissa P, Wurscher Michelle A, Thomas Sushma S, Newman Hana, Hardikar Sheetal, Burnett-Hartman Andrea N
Abstract excerpt
PURPOSE: BRAF mutation and DNA hypermethylation have linked sessile serrated adenomas/polyps (SSA/Ps) to serrated colorectal cancer (CRC) in cross-sectional studies, but they have not been evaluated in a longitudinal study. We aimed to evaluate the associations between molecular markers of serrated polyps and subsequent advanced colorectal neoplasia. METHODS: Study subjects included Kaiser Permanente Washington...
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