Article
DNA Methylation in Colorectal cancer—Impact on Screening and Therapy Monitoring Modalities?
1 Jan 2007
Abstract excerpt
Colorectal cancer (CRC) is a common malignancy. It arises from benign neoplasms and evolves into adenocarcinomas through a stepwise histological progression sequence, proceeding from either adenomas or hyperplastic polyps/serrated adenomas. Genetic alterations have been associated with specific steps in this adenoma-carcinoma sequence and are believed to drive the histological progression of CRC. Recently,...
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