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Article

Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus.

Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2002

Förster Eckart, Tielsch Albrecht, Saum Barbara, Weiss Karl Heinz, Johanssen Celine, Graus-Porta Diana, Müller Ulrich, Frotscher Michael

Abstract excerpt

The extracellular matrix molecule Reelin is required for the correct positioning of neurons during the development of the forebrain. However, the mechanism of Reelin action on neuronal migration is poorly understood. Reelin is assumed to act on neurons directly, but it may also affect the differentiation of glial cells necessary for neuronal migration. Here we show that a regular glial scaffold fails to form in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12244214
DOI: 10.1073/pnas.202035899
PMCID: PMC130606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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