Article
Differences in serum SP-D levels between German and Japanese subjects are associated with SFTPD gene polymorphisms.
BMC medical genetics - 8 Jan 2014
Horimasu Yasushi, Hattori Noboru, Ishikawa Nobuhisa, Tanaka Sonosuke, Bonella Francesco, Ohshimo Shinichiro, Guzman Josune, Costabel Ulrich, Kohno Nobuoki
Abstract excerpt
BACKGROUND: Surfactant protein A (SP-A) and SP-D are clinically established in Japan as serum biomarkers for diagnosing interstitial lung diseases (ILDs). Serum SP-D levels are affected by genetic variants. We conducted the present study to examine whether serum SP-A and/or SP-D levels in healthy subjects (HS) and patients with ILDs differ between populations with different genetic backgrounds. METHODS: German...
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