Article
Genetic and environmental influences of surfactant protein D serum levels.
American journal of physiology. Lung cellular and molecular physiology - 1 May 2006
Sørensen Grith L, Hjelmborg Jacob v B, Kyvik Kirsten O, Fenger Mogens, Høj Anette, Bendixen Christian, Sørensen Thorkild I A, Holmskov Uffe
Abstract excerpt
The collectin surfactant protein D (SP-D) is an important component of the pulmonary innate immune system, but SP-D is also present on extrapulmonary epithelial surfaces and in serum, where it has been used as a biomarker for pulmonary disease states. In this study, we investigate the mechanisms defining the constitutional serum level of SP-D and determine the magnitude of the genetic contribution to serum SP-D...
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