Article
Association of polymorphisms in the human surfactant protein-D (SFTPD) gene and postnatal pulmonary adaptation in the preterm infant.
Acta paediatrica (Oslo, Norway : 1992) - 1 Jan 2009
Hilgendorff Anne, Heidinger Kathrin, Bohnert Anette, Kleinsteiber Anja, König Inke R, Ziegler Andreas, Lindner Ulrike, Frey Georg, Merz Catherine, Lettgen Bernhard, Chakraborty Trinad, Gortner Ludwig, Bein Gregor
Abstract excerpt
BACKGROUND: Surfactant protein-D (SP-D) is a member of the collagenous subfamily of calcium-dependent lectins (collectins). Associations between single nucleotide polymorphisms (SNPs) of the human gene coding surfactant protein-D (SFTPD) and infectious pulmonary diseases have been established by several groups. As the outcome of very preterm infants is mainly determined by pulmonary morbidity, the aim of the...
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