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Article

Neuronal properties of a thyroid C-cell line: partial repression by dexamethasone and retinoic acid.

Molecular endocrinology (Baltimore, Md.) - 1 Feb 1992

Russo A F, Lanigan T M, Sullivan B E

Abstract excerpt

We have analyzed the effect of extracellular stimuli on the differentiation state of the CA77 thyroid C-cell line as a model to understand the control of neural crest cell differentiation. In contrast to the endocrine C-cell phenotype, we found that CA77 cells have a neuronal phenotype characterized by laminin-induced neurites, neuronal antigens, and calcitonin gene-related peptide (CGRP) mRNA expression....

Topics

Animals
Antigens
Calcitonin
Calcitonin Gene-Related Peptide
Cell Adhesion
Cell Differentiation
Cell Line
Cytoplasmic Granules
DNA
Dexamethasone
Neurites
Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

RNA, Messenger

Rats

Thyroid Gland

Tretinoin

Source

Identifiers

PMID: 1569964
DOI: 10.1210/mend.6.2.1569964

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1569964-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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