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Article

In vitro activation of distinct molecular and cellular phenotypes after induction of differentiation in a human neuroblastoma cell line.

Cancer research - 15 Aug 1992

Gaetano C, Matsumoto K, Thiele C J

Abstract excerpt

In this report we provide evidence for the activation of distinct differentiation pathways during treatment of the neuroblastoma cell line SMS-KCNR with 1 mM dibutyryl cyclic AMP (dbcAMP) and/or 5 microM retinoic acid (RA). Our results show that the adrenal gland specific gene pG2 is induced only during dbcAMP treatment, while RA induces a neuronal phenotype and expression of all neural related genes while...

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Identifiers

PMID: 1322787

Genes

SMS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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In vitro activation of distinct molecular and cellular phenotypes after induction of differentiation in a human neuroblastoma cell line.PMID 1322787Read ↗

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p27Kip1: a key mediator of retinoic acid induced growth arrest in the SMS–KCNR human neuroblastoma cell lineSemantic proximity Read ↗

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