Article
Single-nucleotide polymorphism rs948854 in human galanin gene and multiple sclerosis: a gender-specific risk factor.
Journal of neuroscience research - 2 Jan 2017
Lioudyno Victoria, Abdurasulova Irina, Bisaga Gennady, Skulyabin Dmitry, Klimenko Victor
Abstract excerpt
We performed comparative analyses of the genotype distribution and allelic frequencies of the rs948854 polymorphism (G/A) in the galanin gene's promoter in patients with multiple sclerosis (MS) and in healthy matched controls. In total 111 patients and 115 control subjects were included. The analyses revealed that the presence of the minor allele (G) increased susceptibility to MS in men (OR = 2.49, P = 0.008)...
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