Article
Diabetes protection and restoration of thymocyte apoptosis in NOD Idd6 congenic strains.
Diabetes - 1 Jul 2003
Bergman Marie-Louise, Duarte Nadia, Campino Susana, Lundholm Marie, Motta Vinicius, Lejon Kristina, Penha-Gonçalves Carlos, Holmberg Dan
Abstract excerpt
Type 1 diabetes in the nonobese diabetic (NOD) mouse is a multifactorial and polygenic disease. The NOD-derived genetic factors that contribute to type 1 diabetes are named Idd (insulin-dependent diabetes) loci. To date, the biological functions of the majority of the Idd loci remain unknown. We...
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