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Article

Reverse Translational Research of ABCG2 (BCRP) in Human Disease and Drug Response

12 Oct 2017

Abstract excerpt

Reverse translational research takes a bedside-to-bench approach, using sophisticated basic research to explain the biological mechanisms behind observed clinical data. For transporters, which play a role in human disease and drug response, this approach offers a distinct advantage over the typical translational research, which often falters due to inadequate in vitro and preclinical animal models. Research on...

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PMID: 29023674
DOI: 10.1002/cpt.903

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