Article
Genotype variability and haplotype frequency of MDR1 (ABCB1) gene polymorphism in Morocco.
DNA and cell biology - 1 Oct 2013
Kassogue Yaya, Dehbi Hind, Nassereddine Sanaa, Quachouh Meryem, Nadifi Sellama
Abstract excerpt
The multidrug resistance gene (MDR1) plays an important role in the transport of a wide range of drugs and elimination of xenobiotics from the body. Identification of polymorphisms and haplotypes in the MDR1 gene might not only help understand pharmacokinetics and pharmacodynamics of drugs, but also can help in the prediction of drug responses, toxicity, and side effects, especially, in the era of personalized...
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