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Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations.

Pharmacogenetics - 1 Aug 2002

Tang Kun, Ngoi Soo-Mun, Gwee Pai-Chung, Chua John M Z, Lee Edmund J D, Chong Samuel S, Lee Caroline G L

Abstract excerpt

The MDR1 multidrug transporter plays a key role in determining drug bioavailability, and differences in drug response exist amongst different ethnic groups. Numerous studies have identified an association between the MDR1 single nucleotide polymorphism (SNP) exon 26 3435C>T and differences in MDR1 function. We performed a haplotype analysis of the MDR1 gene in three major ethnic groups (Chinese, Malays and...

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PMID: 12172212
DOI: 10.1097/00008571-200208000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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