Article
p97 Is in a complex with cholera toxin and influences the transport of cholera toxin and related toxins to the cytoplasm.
The Journal of biological chemistry - 22 Apr 2005
Abujarour Ramzey J, Dalal Seema, Hanson Phyllis I, Draper Rockford K
Abstract excerpt
Certain protein toxins, including cholera toxin, ricin, and Pseudomonas aeruginosa exotoxin A, are transported to the lumen of the endoplasmic reticulum where they retro-translocate across the endoplasmic reticulum membrane to enter the cytoplasm. The mechanism of retrotranslocation is poorly understood but may involve the endoplasmic reticulum-associated degradation pathway. The AAA ATPase p97 (also called...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
