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Article

Structure and function of the AAA+ ATPase p97/Cdc48p.

Gene - 25 May 2016

Xia Di, Tang Wai Kwan, Ye Yihong

Abstract excerpt

p97 (also known as valosin-containing protein (VCP) in mammals or Cdc48p in Saccharomyces cerevisiae) is an evolutionarily conserved ATPase present in all eukaryotes and archaebacteria. In conjunction with a collection of cofactors and adaptors, p97/Cdc48p performs an array of biological functions mostly through modulating the stability of 'client' proteins. Using energy from ATP hydrolysis, p97/Cdc48p segregates...

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Source

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Identifiers

PMID: 26945625
DOI: 10.1016/j.gene.2016.02.042
PMCID: PMC4821690

Genes

VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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