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Article

seven-up Controls switching of transcription factors that specify temporal identities of Drosophila neuroblasts.

Developmental cell - 1 Feb 2005

Kanai Makoto I, Okabe Masataka, Hiromi Yasushi

Abstract excerpt

Drosophila neuronal stem cell neuroblasts (NB) constantly change character upon division, to produce a different type of progeny at the next division. Transcription factors Hunchback (HB), Krüppel (KR), Pdm (PDM), etc. are expressed sequentially in each NB and act as determinants of birth-order identity. How a NB switches its expression profile from one transcription factor to the next is poorly understood. We...

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PMID: 15691762
DOI: 10.1016/j.devcel.2004.12.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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