Article
The Drosophila seven-up gene, a member of the steroid receptor gene superfamily, controls photoreceptor cell fates.
Cell - 26 Jan 1990
Mlodzik M, Hiromi Y, Weber U, Goodman C S, Rubin G M
Abstract excerpt
The Drosophila seven-up (svp) gene was isolated as a lethal insertion in an "enhancer trap" screen. It is expressed and required in photoreceptor cell precursors R1, R3, R4, and R6 during eye development. The absence of svp+ function causes a transformation of these cells toward an R7 cell fate, as judged by morphology and expression of an R7-specific marker. This transformation depends in part on the sevenless...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA, Recombinant
- Drosophila
- Gene Expression
- Genes
- Genomic Library
- Molecular Sequence Data
- Mosaicism
- Multigene Family