Article
Cellular diversity in the developing nervous system: a temporal view from Drosophila.
Development (Cambridge, England) - 1 Aug 2002
Brody Thomas, Odenwald Ward F
Abstract excerpt
This article considers the evidence for temporal transitions in CNS neural precursor cell gene expression during development. In Drosophila, five prospective competence states have so far been identified, characterized by the successive expression of Hb-->Kr-->Pdm-->Cas-->Gh in many, but not all, neuroblasts. In each temporal window of transcription factor expression, the neuroblast generates sublineages whose...
Topics
- Animals
- Cell Cycle
- Cell Differentiation
- Cell Transplantation
- Central Nervous System
- Drosophila
- Feedback
- Gene Expression Regulation, Developmental
- Genes, Insect
- Genes, Regulator
- Mutation