Article
Regulation of neuroblast competence in Drosophila.
Nature - 9 Oct 2003
Pearson Bret J, Doe Chris Q
Abstract excerpt
Individual neural progenitors generate different cell types in a reproducible order in the retina, cerebral cortex and probably in the spinal cord. It is unknown how neural progenitors change over time to generate different cell types. It has been proposed that progenitors undergo progressive restriction or transit through distinct competence states; however, the underlying molecular mechanisms remain unclear....
Topics
- Animals
- Cell Differentiation
- Cell Lineage
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Mitosis
- Neuronal Plasticity
- Neurons
- Phenotype
- Stem Cells
- Time Factors
- Transcription Factors