Article
Seven up acts as a temporal factor during two different stages of neuroblast 5-6 development.
Development (Cambridge, England) - 1 Dec 2011
Benito-Sipos Jonathan, Ulvklo Carina, Gabilondo Hugo, Baumgardt Magnus, Angel Anna, Torroja Laura, Thor Stefan
Abstract excerpt
Drosophila embryonic neuroblasts generate different cell types at different time points. This is controlled by a temporal cascade of Hb→Kr→Pdm→Cas→Grh, which acts to dictate distinct competence windows sequentially. In addition, Seven up (Svp), a member of the nuclear hormone receptor family, acts early in the temporal cascade, to ensure the transition from Hb to Kr, and has been referred to as a 'switching...
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