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Article

Plasmalogens as endogenous antioxidants: somatic cell mutants reveal the importance of the vinyl ether.

The Biochemical journal - 15 Mar 1999

Zoeller R A, Lake A C, Nagan N, Gaposchkin D P, Legner M A, Lieberthal W

Abstract excerpt

Exposure of plasmalogen-deficient variants of the murine cell line RAW 264.7 to short-term (0-100 min) treatment with electron transport inhibitors antimycin A or cyanide (chemical hypoxia) resulted in a more rapid loss of viability than in the parent strain. Results suggested that plasmalogen-deficient cells were more sensitive to reactive oxygen species (ROS) generated during chemical hypoxia; the mutants could...

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PMID: 10051451
PMCID: PMC1220115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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