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Article

Alterations of fatty acid metabolism and membrane fluidity in peroxisome-defective mutant ZP102 cells.

Lipids - 1 Jan 2004

Nagura Michiaki, Saito Makiko, Iwamori Masao, Sakakihara Yoichi, Igarashi Takashi

Abstract excerpt

We investigated lipid composition and FA metabolism in Chinese hamster ovary CHO-K1) cells and Pex5-mutated CHO-K1 (ZP102) cells to clarify the biochemical bases of peroxisome biogenesis disorders (PBD). ZP102 cells have defective peroxisomes and exhibit impairments of peroxisomal beta-oxidation of FA and plasmalogen biosynthesis. In addition, we identified FA metabolic alterations in the synthesis of several...

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PMID: 15055234
DOI: 10.1007/s11745-004-1200-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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