Article
Animal cell mutants unable to take up biologically active glycerophospholipids.
Journal of lipid research - 1 Sept 1995
Zoeller R A, Layne M D, Modest E J
Abstract excerpt
We have isolated two mutant strains from the murine, macrophage-like cell line, RAW 264.7, that are resistant to the cytotoxic effects of the antineoplastic, platelet activating factor analogue, 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OMe). The mutants were isolated using a singl...
Topics
- Animals
- Cell Line
- Drug Resistance
- Endocytosis
- Glycerophosphates
- Glycerylphosphorylcholine
- Lysophosphatidylcholines
- Lysophospholipids
- Macrophages
- Mice
- Mutation
- Phosphatidic Acids
- Phospholipid Ethers