Article
Animal cell mutants unable to take up biologically active glycerophospholipids.
Journal of lipid research - 1 Sept 1995
Zoeller R A, Layne M D, Modest E J
Abstract excerpt
We have isolated two mutant strains from the murine, macrophage-like cell line, RAW 264.7, that are resistant to the cytotoxic effects of the antineoplastic, platelet activating factor analogue, 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OMe). The mutants were isolated using a single round of selection to ensure that resistance was due to a single gene defect. These mutants, RAW.R1 and RAW.R23, are...
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