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Article

Bayes empirical bayes inference of amino acid sites under positive selection.

Molecular biology and evolution - 1 Apr 2005

Yang Ziheng, Wong Wendy S W, Nielsen Rasmus

Abstract excerpt

Codon-based substitution models have been widely used to identify amino acid sites under positive selection in comparative analysis of protein-coding DNA sequences. The nonsynonymous-synonymous substitution rate ratio (d(N)/d(S), denoted omega) is used as a measure of selective pressure at the protein level, with omega > 1 indicating positive selection. Statistical distributions are used to model the variation in...

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PMID: 15689528
DOI: 10.1093/molbev/msi097

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NEB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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