Article
Detecting positively selected amino acid sites using posterior predictive P-values.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2002
Nielsen R, Huelsenbeck J P
Abstract excerpt
Identifying positively selected amino acid sites is an important approach for making inference about the function of proteins; an amino acid site that is undergoing positive selection is likely to play a key role in the function of the protein. We present a new Bayesian method for identifying positively selected amino acid sites and apply the method to a data set of hemagglutinin sequences from the Influenza...
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