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New Microtubule / Tubulin-Targeted Anticancer Drugs and Novel Chemotherapeutic Strategies

1 Nov 2004

Abstract excerpt

The clinical success of the taxanes and the vinca alkaloids has sparked a major search for new drugs that perturb mitotic spindle microtubule dynamics and function, yielding a large number of promising compounds. A potential valuable strategy would be to use core microtubule-targeted drugs along with novel targeted drug therapies as they are developed, where the antitumor activity of a targeted drug can be...

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PMID: 15688618
DOI: 10.1179/joc.2004.16.supplement-1.83

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