Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting Microtubules for Cancer Chemotherapy

1 Jan 2005

Abstract excerpt

Chemical compounds that interfere with microtubules such as the vinca alkaloids and taxanes are important chemotherapeutic agents for the treatment of cancer. As our knowledge of microtubule-targeting drugs increases, we realize that the mechanism underlying the anti-cancer activity of these agents may mainly lie in their inhibitory effects on spindle microtubule dynamics, rather than in their effects on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Treatment and Pharmacology
Share to Chemical Reactions and Isotopes
Share to Microtubule and mitosis dynamics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15720262
DOI: 10.2174/1568011053352569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting Microtubules for Cancer ChemotherapyPMID 15720262Read ↗

Targeting Microtubules by Natural Agents for Cancer TherapySemantic proximity Read ↗

Microtubule inhibitors: Differentiating tubulin-inhibiting agents based on mechanisms of action, clinical activity, and resistanceSemantic proximity Read ↗

New Microtubule / Tubulin-Targeted Anticancer Drugs and Novel Chemotherapeutic StrategiesSemantic proximity Read ↗

How Do Microtubule-Targeted Drugs Work? An OverviewSemantic proximity Read ↗

Microtubules: A dynamic target in cancer therapySemantic proximity Read ↗

Microtubule Targeting Agents in Disease: Classic Drugs, Novel RolesSemantic proximity Read ↗

Microtubule-Targeting Drugs: More than AntimitoticsSemantic proximity Read ↗

How do anti-mitotic drugs kill cancer cells?Semantic proximity Read ↗

The Elephant in the Room: The Role of Microtubules in Cancer.Semantic proximity Read ↗

Microtubules and Cell Division: Potential Pharmacological Targets in Cancer TherapySemantic proximity Read ↗

Hitting the brakes: targeting microtubule motors in cancerSemantic proximity Read ↗

Microtubule Active Agents: Beyond the Taxane FrontierSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.