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Article

Microtubules: A dynamic target in cancer therapy

19 Feb 2008

Abstract excerpt

The tubulin/microtubule system is an important target for anticancer therapy. Two of the most clinically valuable groups of these agents are the vinca alkaloids and taxanes. In recent years, new tubulin-binding agents have been under preclinical or clinical development. One of these classes of agents, epothilones, has shown great promise in phase III clinical trials. What all these agents share in common, is that...

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PMID: 18380008
DOI: 10.1002/iub.25

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