Article
New genes with roles in the C. elegans embryo revealed using RNAi of ovary-enriched ORFeome clones.
Genome research - 1 Feb 2005
Fernandez Anita G, Gunsalus Kristin C, Huang Jerry, Chuang Ling-Shiang, Ying Nancy, Liang Hsiao-Lan, Tang Caroline, Schetter Aaron J, Zegar Charles, Rual Jean-François, Hill David E, Reinke Valerie, Vidal Marc, Piano Fabio
Abstract excerpt
Several RNA interference (RNAi)-based functional genomic projects have been performed in Caenorhabditis elegans to identify genes required during embryogenesis. These studies have demonstrated that the ovary is enriched for transcripts essential for the first cell divisions. However, comparing RNAi results suggests that many genes involved in embryogenesis have yet to be identified, especially those eliciting...
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