Article
Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library.
Genome research - 1 Oct 2004
Rual Jean-François, Ceron Julian, Koreth John, Hao Tong, Nicot Anne-Sophie, Hirozane-Kishikawa Tomoko, Vandenhaute Jean, Orkin Stuart H, Hill David E, van den Heuvel Sander, Vidal Marc
Abstract excerpt
The recently completed Caenorhabditis elegans genome sequence allows application of high-throughput (HT) approaches for phenotypic analyses using RNA interference (RNAi). As large phenotypic data sets become available, "phenoclustering" strategies can be used to begin understanding the complex molecular networks involved in development and other biological processes. The current HT-RNAi resources represent a...
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