Article
Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.
Nature - 24 Mar 2005
Sönnichsen B, Koski L B, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume A-M, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Röder M, Finell J, Häntsch H, Jones S J M, Jones M, Piano F, Gunsalus K C, Oegema K, Gönczy P, Coulson A, Hyman A A, Echeverri C J
Abstract excerpt
A key challenge of functional genomics today is to generate well-annotated data sets that can be interpreted across different platforms and technologies. Large-scale functional genomics data often fail to connect to standard experimental approaches of gene characterization in individual laboratories. Furthermore, a lack of universal annotation standards for phenotypic data sets makes it difficult to compare...
Topics
- Animals
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Computational Biology
- Embryonic Development
- Genes, Helminth
- Genome
- Genomics
- Phenotype