Article
DTL, the Drosophila homolog of PIMT/Tgs1 nuclear receptor coactivator-interacting protein/RNA methyltransferase, has an essential role in development.
The Journal of biological chemistry - 1 Apr 2005
Komonyi Orbán, Pápai Gábor, Enunlu Izzet, Muratoglu Selen, Pankotai Tibor, Kopitova Darija, Maróy Péter, Udvardy Andor, Boros Imre
Abstract excerpt
We describe a novel Drosophila gene, dtl (Drosophila Tat-like), which encodes a 60-kDa protein with RNA binding activity and a methyltransferase (MTase) domain. Dtl has an essential role in Drosophila development. The homologs of DTL recently described include PIMT (peroxisome proliferator-activated receptor-interacting protein with a methyltransferase domain), an RNA-binding protein that interacts with and...
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