Article
drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia.
Genes & development - 1 Jan 1995
Anderson M G, Perkins G L, Chittick P, Shrigley R J, Johnson W A
Abstract excerpt
The Drosophila drifter (dfr) gene, previously referred to as Cf1a, encodes a POU-domain DNA-binding protein implicated as a neuron-specific regulator in the developing central nervous system (CNS). We have isolated full-length dfr cDNA clones that encode a 46-kD protein containing the conserved POU-domain DNA-binding domain. The use of alternate polyadenylation sites produces two dfr mRNA transcripts that are...
Topics
- Animals
- Cell Differentiation
- Cell Movement
- DNA-Binding Proteins
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression
- Genes, Insect
- Genes, Lethal
- Immunohistochemistry
- Mutation
