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Article

Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition.

PLoS genetics - 1 Mar 2017

Fan Wei, Lam Sin Man, Xin Jingxue, Yang Xiao, Liu Zhonghua, Liu Yuan, Wang Yong, Shui Guanghou, Huang Xun

Abstract excerpt

The general transcription factor TBP (TATA-box binding protein) and its associated factors (TAFs) together form the TFIID complex, which directs transcription initiation. Through RNAi and mutant analysis, we identified a specific TBP family protein, TRF2, and a set of TAFs that regulate lipid droplet (LD) size in the Drosophila larval fat body. Among the three Drosophila TBP genes, trf2, tbp and trf1, only loss...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28273089
DOI: 10.1371/journal.pgen.1006664
PMCID: PMC5362240

Genes

TAF9
TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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