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Article

Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.

Mechanisms of development - 1 Jan 2000

Jia Yuzhi, Viswakarma Navin, Crawford Susan E, Sarkar Joy, Sambasiva Rao M, Karpus William J, Kanwar Yashpal S, Zhu Yi-Jun, Reddy Janardan K

Abstract excerpt

PIMT (also known as PIPMT/NCOA6IP/Tgs1), first isolated as a transcription coactivator PRIP (NCOA6)-interacting 96-kDa protein with RNA-binding property, possesses RNA methyltransferase activity. As a transcription coactivator binding protein, PIMT enhances the nuclear receptor transcriptional ac...

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Source

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Identifiers

PMID: 22982455
DOI: 10.1016/j.mod.2012.08.002
PMCID: PMC3503541

Genes

NCOA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22982455-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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