Article
Chromosome looping in yeast: telomere pairing and coordinated movement reflect anchoring efficiency and territorial organization.
The Journal of cell biology - 31 Jan 2005
Bystricky Kerstin, Laroche Thierry, van Houwe Griet, Blaszczyk Marek, Gasser Susan M
Abstract excerpt
Long-range chromosome organization is known to influence nuclear function. Budding yeast centromeres cluster near the spindle pole body, whereas telomeres are grouped in five to eight perinuclear foci. Using live microscopy, we examine the relative positions of right and left telomeres of several yeast chromosomes. Integrated lac and tet operator arrays are visualized by their respective repressor fused to CFP...
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