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Article

Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions.

PLoS genetics - 1 May 2009

Miele Adriana, Bystricky Kerstin, Dekker Job

Abstract excerpt

The organization of eukaryotic genomes is characterized by the presence of distinct euchromatic and heterochromatic sub-nuclear compartments. In Saccharomyces cerevisiae heterochromatic loci, including telomeres and silent mating type loci, form clusters at the nuclear periphery. We have employed live cell 3-D imaging and chromosome conformation capture (3C) to determine the contribution of nuclear positioning...

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Share to Chromosomes, Fungal
Share to Gene Silencing
Share to Genes, Mating Type, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heterochromatin

Share to Imaging, Three-Dimensional

Share to Nucleosomes

Share to Silencer Elements, Transcriptional

Share to Silent Information Regulator Proteins, Saccharomyces cerevisiae

Source

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Identifiers

PMID: 19424429
DOI: 10.1371/journal.pgen.1000478
PMCID: PMC2673037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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