Nuclear organization and transcriptional silencing in yeast.

doi:10.1007/BF01952113

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Article

Nuclear organization and transcriptional silencing in yeast.

Experientia - 15 Dec 1996

Gotta M, Gasser S M

Abstract excerpt

Transcriptional repression at the yeast silent mating type loci requires the formation of a nucleoprotein complex at specific cis-acting elements called silencers, which in turn promotes the binding of a histone-associated Sir-protein complex to adjacent chromatin. A similar mechanism of long-ran...

Topics

Cell Nucleus
Chromatin
Fluorescent Antibody Technique
Histones
In Situ Hybridization
Models, Molecular
Mutation
Nuclear Proteins
Telomere
Transcription, Genetic
Yeasts

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