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Article

Detection of rare and novel EGFR mutations in NSCLC patients: Implications for treatment-decision.

Lung cancer (Amsterdam, Netherlands) - 1 Jan 2020

Sousa A C, Silveira C, Janeiro A, Malveiro S, Oliveira A R, Felizardo M, Nogueira F, Teixeira E, Martins J, Carmo-Fonseca M

Abstract excerpt

OBJECTIVES: Mutations in the gene that encodes epidermal growth factor receptor (EGFR) are biomarkers that predict how non-small cell lung cancer (NSCLC) patients respond to EGFR-targeted therapies collectively known as tyrosine kinase inhibitors (TKIs). Thus, EGFR genotyping provides crucial information for treatment decision. Both Sanger sequencing and real-time PCR methodologies are used for EGFR genotyping....

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PMID: 31715539
DOI: 10.1016/j.lungcan.2019.10.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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