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Article

Rab8 regulates the actin-based movement of melanosomes.

Molecular biology of the cell - 1 Apr 2005

Chabrillat Marion L, Wilhelm Claire, Wasmeier Christina, Sviderskaya Elena V, Louvard Daniel, Coudrier Evelyne

Abstract excerpt

Rab GTPases have been implicated in the regulation of specific microtubule- and actin-based motor proteins. We devised an in vitro motility assay reconstituting the movement of melanosomes on actin bundles in the presence of ATP to investigate the role of Rab proteins in the actin-dependent movement of melanosomes. Using this assay, we confirmed that Rab27 is required for the actin-dependent movement of...

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Identifiers

PMID: 15673612
DOI: 10.1091/mbc.e04-09-0770
PMCID: PMC1073648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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