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Article

Rab27a regulates the peripheral distribution of melanosomes in melanocytes.

The Journal of cell biology - 19 Feb 2001

Hume A N, Collinson L M, Rapak A, Gomes A Q, Hopkins C R, Seabra M C

Abstract excerpt

Rab GTPases are regulators of intracellular membrane traffic. We report a possible function of Rab27a, a protein implicated in several diseases, including Griscelli syndrome, choroideremia, and the Hermansky-Pudlak syndrome mouse model, gunmetal. We studied endogenous Rab27a and overexpressed enhanced GFP-Rab27a fusion protein in several cultured melanocyte and melanoma-derived cell lines. In pigmented cells, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11266470
DOI: 10.1083/jcb.152.4.795
PMCID: PMC2195786

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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