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Article

Zebrafish eda and edar mutants reveal conserved and ancestral roles of ectodysplasin signaling in vertebrates.

PLoS genetics - 3 Oct 2008

Harris Matthew P, Rohner Nicolas, Schwarz Heinz, Perathoner Simon, Konstantinidis Peter, Nüsslein-Volhard Christiane

Abstract excerpt

The genetic basis of the development and variation of adult form of vertebrates is not well understood. To address this problem, we performed a mutant screen to identify genes essential for the formation of adult skeletal structures of the zebrafish. Here, we describe the phenotypic and molecular characterization of a set of mutants showing loss of adult structures of the dermal skeleton, such as the rays of the...

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Identifiers

PMID: 18833299
DOI: 10.1371/journal.pgen.1000206
PMCID: PMC2542418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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