Article
Ectodysplasin signaling in development.
Cytokine & growth factor reviews - 1 Jan 2000
Mikkola Marja L, Thesleff Irma
Abstract excerpt
Ectodysplasin (Eda), a signaling molecule belonging to the tumor necrosis factor family, is required for normal development of several ectodermally derived organs in humans and mice. Two closely related isoforms of ectodysplasin, Eda-A1 and Eda-A2, have been described which bind to and activate two different receptors, Edar and X-linked Eda-A2 receptor (Xedar), respectively. Mutations in Eda, Edar or other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.