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Article

E-cadherin intron 2 contains cis-regulatory elements essential for gene expression.

Development (Cambridge, England) - 1 Mar 2005

Stemmler Marc P, Hecht Andreas, Kemler Rolf

Abstract excerpt

Cadherin-mediated cell-cell adhesion plays important roles in mouse embryonic development, and changes in cadherin expression are often linked to morphogenetic events. For proper embryonic development and organ formation, the expression of E-cadherin must be tightly regulated. Dysregulated expression during tumorigenesis confers invasiveness and metastasis. Except for the E-box motifs in the E-cadherin promoter,...

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Identifiers

PMID: 15673570
DOI: 10.1242/dev.01662

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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