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Article

Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2017

Lee Heon-Woo, Chong Diana C, Ola Roxana, Dunworth William P, Meadows Stryder, Ka Jun, Kaartinen Vesa M, Qyang Yibing, Cleaver Ondine, Bautch Victoria L, Eichmann Anne, Jin Suk-Won

Abstract excerpt

OBJECTIVE: Increasing evidence suggests that bone morphogenetic protein (BMP) signaling regulates angiogenesis. Here, we aimed to define the function of BMP receptors in regulating early postnatal angiogenesis by analysis of inducible, endothelial-specific deletion of the BMP receptor components Bmpr2 (BMP type 2 receptor), Alk1 (activin receptor-like kinase 1), Alk2, and Alk3 in mouse retinal vessels. APPROACH...

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Share to Activin Receptors, Type I
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28232325
DOI: 10.1161/ATVBAHA.116.308422
PMCID: PMC5382795

Genes

ACVR1
BMPR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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