Article
Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 14 Oct 2009
Riesenberg Amy N, Liu Zhenyi, Kopan Raphael, Brown Nadean L
Abstract excerpt
Vertebrate retinal progenitor cells (RPCs) are pluripotent, but pass through competence states that progressively restrict their developmental potential (Cepko et al., 1996; Livesey and Cepko, 2001; Cayouette et al., 2006). In the rodent eye, seven retinal cell classes differentiate in overlapping waves, with RGCs, cone photoreceptors, horizontals, and amacrines forming predominantly before birth, and rod...
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