Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental, molecular, and genetic dissection of INa in vivo in embryonic zebrafish sensory neurons.

Journal of neurophysiology - 1 Jun 2005

Pineda Ricardo H, Heiser Ryan A, Ribera Angeles B

Abstract excerpt

The presence of multiple Nav1 isotypes within a neuron and the lack of specific blockers hamper identification of the in vivo roles of sodium current (INa) components, especially during embryonic stages. To identify the functional properties of INa components in vivo in developing neurons, we took a molecular genetic approach. Embryonic zebrafish Rohon-Beard (RB) mechanosensory neurons express two different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Microinjections
Share to Neurons, Afferent
Share to Oligodeoxyribonucleotides, Antisense

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Reaction Time

Share to Sodium Channel Blockers

Share to Sodium Channels

Share to Spinal Cord

Share to Tetrodotoxin

Source

Identifiers

PMID: 15673553
DOI: 10.1152/jn.01070.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental, molecular, and genetic dissection of INa in vivo in embryonic zebrafish sensory neurons.PMID 15673553Read ↗

Zebrafish touch-insensitive mutants reveal an essential role for the developmental regulation of sodium current.Semantic proximity Read ↗

Na <sub>V</sub> 1.1 is essential for proprioceptive signaling and motor behaviorsSemantic proximity Read ↗

Two distinct mechanisms for Na <sub>v</sub> 1.7 null analgesiaSemantic proximity Read ↗

Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate.Semantic proximity Read ↗

Deletion of voltage-gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system.Semantic proximity Read ↗

Analysis of the activity-deprived zebrafish mutant macho reveals an essential requirement of neuronal activity for the development of a fine-grained visuotopic map.Semantic proximity Read ↗

Development of skeletal muscle sodium and potassium currents in zebrafish sofa potato mutants.Semantic proximity Read ↗

RNA editing generates tissue-specific sodium channels with distinct gating properties.Semantic proximity Read ↗

Silencing the Spark: CRISPR/Cas9 Genome Editing in Weakly Electric Fish.Semantic proximity Read ↗

K+ channel distribution and clustering in developing and hypomyelinated axons of the optic nerve.Semantic proximity Read ↗

Molecular genetic dissection of the zebrafish olfactory system.Semantic proximity Read ↗

The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.