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Article

The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish.

American journal of physiology. Heart and circulatory physiology - 1 Oct 2001

Warren K S, Baker K, Fishman M C

Abstract excerpt

Genetic studies in zebrafish have focused on embryonic mutations, but many physiological mechanisms continue to mature after embryogenesis. We report here that zebrafish homozygous for the mutation slow mo can be raised to adulthood. In the embryo, the slow mo gene is needed to regulate heart rate, and its mutation causes a reduction in pacemaker current (I(h)) and slowing of heart rate (bradycardia). The...

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Identifiers

PMID: 11557562
DOI: 10.1152/ajpheart.2001.281.4.H1711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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