Article

Na <sub>V</sub> 1.1 is essential for proprioceptive signaling and motor behaviors

2022-05-06

Abstract excerpt

<h4> A bstract </h4> The voltage-gated sodium channel (Na V ), Na V 1.1, is well-studied in the central nervous system; conversely, its contribution to peripheral sensory neuron function is more enigmatic. Here, we identify a new role for Na V 1.1 in mammalian proprioception. RNAscope analysis and in vitro patch clamp recordings in genetically identified mouse proprioceptors show ubiquitously channel expres...

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Literature Corpus work: 8e9ec290-0751-5b23-a777-79e4ddae4294
DOI: 10.1101/2022.05.05.490851

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