Article
Defective "pacemaker" current (Ih) in a zebrafish mutant with a slow heart rate.
Proceedings of the National Academy of Sciences of the United States of America - 29 Apr 1997
Baker K, Warren K S, Yellen G, Fishman M C
Abstract excerpt
At a cellular level, cardiac pacemaking, which sets the rate and rhythm of the heartbeat, is produced by the slow membrane depolarization that occurs between action potentials. Several ionic currents could account for this pacemaker potential, but their relative prominence is controversial, and it is not known which ones actually play a pacemaking role in vivo. To correlate currents in individual heart cells with...
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